Effectiveness of a single fixed dose of rasburicase 3 mg in the management of tumour lysis syndrome
نویسندگان
چکیده
منابع مشابه
The Efficacy of Single Dose Rasburicase in Prevention or Treatment of Tumor Lysis Syndrome in Children
Background: Tumor lysis syndrome (TLS) is a major metabolic complication in patients with malignancy after initiation of chemotherapy or spontaneously without treatment. The role of Rasburicase (a recombinant urate-oxidase enzyme) in prevention and treatment of TLS has been demonstrated in recent years. We aimed to investigate the efficacy of a single dose of rasburicase in reducing the risk of...
متن کاملSingle-dose rasburicase 6 mg in the management of tumor lysis syndrome in adults.
Rasburicase is currently approved at a dosage of 0.15-0.2 mg/kg once/day for 5 days in pediatric patients with cancer to lower plasma uric acid concentrations and manage tumor lysis syndrome (TLS). Information on rasburicase dosing in adults is limited, with some data on using rasburicase as a single dose instead of multiple daily doses. Therefore, we evaluated the efficacy of a single dose of ...
متن کاملthe efficacy of single dose rasburicase in prevention or treatment of tumor lysis syndrome in children
background: tumor lysis syndrome (tls) is a major metabolic complication in patients with malignancy after initiation of chemotherapy or spontaneously without treatment. the role of rasburicase (a recombinant urate-oxidase enzyme) in prevention and treatment of tls has been demonstrated in recent years. we aimed to investigate the efficacy of a single dose of rasburicase in reducing the risk of...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2013
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2012.04355.x